Publications

PRDM14 Overexpression & Proof of Principle: RNAi of PRDM14 in Breast Cancer

January 3, 2014

There are 16 PRDM proteins, many of which are known as master epigenetic regulators of cellular differentiation, especially in hematopoietic, epithelial and neural cells. The PRDMs are also known for driving the development of specialized cells, such as antibody secreting plasma cells and conferring...

Induction of apoptosis in plasma cells by B lymphocyte-induced maturation protein-1 knockdown

March 31, 2013

B lymphocyte-induced maturation protein-1 (Blimp-1) is a transcriptional repressor that plays an important role during plasmacytic differentiation and is expressed in normal and transformed plasma cells. We here investigated the importance of continuous Blimp-1 expression. We found that knockdown of...